Hexanoic acid, 2-ethyl-, C12-15-alkyl esters

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

29 Dec 2017 - 9 Feb 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

27 July 1995

Deviations:

no

GLP compliance:

no

Other quality assurance:

other: ISO 9001: 2015

Type of method:

flask method

Key result

Water solubility:

< 0.2 mg/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

>= 7.3 - <= 7.7

Details on results:

Preliminary Test     
The content of test item dissolved in the water sample was < 0.20 mg/L.

Main Study     
The results for the samples taken at 24, 48 and 72 hours at a loading rate of 8.6 mg/L and 86 mg/L are given inTable 4andTable 5, respectively.
No test item was detected at either loading rate. The analyzed concentrations are therefore reported to be below the lowest calibration standard, multiplied by the dilution factor.
No test item was detected in the pretreated sample from the blank water mixture.
Since no test item was measured in the samples from the main test, the undissolved part was checked. From this, it was concluded that the right test item was used. 

Table 4          
Main study - water solubility of the test item at a loading rate of 8.6 mg/L

Stirring time [hours]	Analyzed concentration^1 [mg/L]	Mean^1 [mg/L]	Maximum difference [%]	pH
24	< 0.20	< 0.20	n.a.	7.4
48	< 0.20			7.7
72	< 0.20			7.6

¹       The concentration was below the lowest calibration standard, taking the dilution factor of 0.33 into account.

n.a.  Not applicable.

Table 5          
Main study - water solubility of the test item at a loading rate of 86 mg/L

Stirring time [hours]		Analyzed concentration^1 [mg/L]		Mean^1 [mg/L]		Maximum difference [%]		pH
24		< 0.20		< 0.20		n.a.		7.5
48		< 0.20						7.4
72		< 0.20						7.3

¹       The concentration was below the lowest calibration standard, taking the dilution factor of 0.33 into account.

n.a.  Not applicable.

 

Conclusions:

The water solubility of the test substance was found to be < 0.2 mg/l at 20 °C, under the conditions of the test.

Executive summary:

In this guideline (OECD 105) study, the water solubility of the test substance was found to be < 0.2 mg/l at 20 °C.

Description of key information

Study conducted to recognised testing guidelines.

Additional information

Water solubility < 0.2 mg/L @ 20 °C, water pH 7.3 - 7.7