Registration Dossier
Registration Dossier
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EC number: 210-112-3 | CAS number: 606-28-0
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The substance has a half life of 70.8 days at pH 7 and 25 °C. At pH 7 and 15°C, the half-life of the substance is 243 days.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 70.8 d
- at the temperature of:
- 25 °C
Additional information
In the Tier 1 study, hydrolysis of the test item was followed over 5 days at 50 °C at pH values of 4, 7 and 9. The Tier 1 study indicated that RCX 14-672 is stable at pH 4, but hydrolyses at pH 7 and 9.
In the Tier 2 study, the half-lives of RCX 14-672 were determined for the pH values, where the test item was unstable in the Tier 1 study. Tier 2 was run at 50, 25 and 15 °C, at pH 7 and 9, and hydrolysis was monitored for a maximum of 30 days or until 90% hydrolysis was observed. Hydrolysis was fastest at pH 9 and 50°C, and slowest at pH 7 and 15°C.
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