Registration Dossier
Registration Dossier
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EC number: 203-941-7 | CAS number: 112-16-3
Endpoint summary
Administrative data
Description of key information
This substance is corrosive so acute toxicity testing can be waived. Additionally, this substance is an on-site isolated intermediate and therefore additional testing is not warranted. A K4 oral study is available concluding GHS Cat 5 oral. A K4 inhalation study is available that does not provide a conclusion on classification.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is classified as corrosive to the skin
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Link to relevant study records
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is classified as corrosive to the skin
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Link to relevant study records
- Endpoint:
- acute toxicity: dermal
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is classified as corrosive to the skin
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Only study summaries are available. The documentation is insufficient for assessement.
The acute oral LD50 (rat) was reported to be 3220 mg/kg
The inhalation LC50 (rat) was reported to be > 0.16 mg/l air (nominal)
Justification for classification or non-classification
This substance is corrosive so acute toxicity testing can be waived. Additionally, this substance is an on-site isolated intermediate and therefore additional testing is not warranted. A K4 oral study is available concluding GHS Cat 5 oral. A K4 inhalation study is available that does not provide a conclusion on classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
