Registration Dossier
Registration Dossier
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EC number: 203-941-7 | CAS number: 112-16-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: no data available
Hydrolysis product lauric acid: Acutely toxic to aquatic invertebrates.
Hydrolysis product HCl: Acutely very toxic for aquatic invertebrates (pH-dependent).
Key value for chemical safety assessment
Additional information
Parent compound lauroyl chloride:
No data are available for lauroyl chloride (CAS 112 -16 -3). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and lauric acid (CAS 143 -07 -7). Therefore, the short-term toxicity to aquatic invertebrates is assessed on the basis of data on lauric acid (CAS 143 -07 -7).
One reliable experimental result is available for the hydrolysis product lauric acid (CAS 143 -07 -7). The study was performed with Daphnia magna as test species according to OECD 202. Detailed documentation is available only in Japanese, but the information are from a reliable source (NITE 2011/2012; study performed in 1999). The 48 -h EC50 was determined to be 3.6 mg/L. Although not specified, the pH was most likely not adjusted. The ECHA Registration Dossier for lauric acid lists a 48 -h EC50 of 3.6 mg/L (no info on pH; with dispersant; test concentrations analytically verified; ECHA, 2012). It must be concluded that lauric acid is acutely toxic to aquatic invertebrates.
Hydrolysis product hydrochloric acid (HCl):
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 202 with Daphnia magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; OECD 2002).
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