Registration Dossier
Registration Dossier
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EC number: 206-119-6 | CAS number: 302-23-8
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 1195
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Hydroxyprogesterone acetate
- EC Number:
- 206-119-6
- EC Name:
- Hydroxyprogesterone acetate
- Cas Number:
- 302-23-8
- Molecular formula:
- C23H32O4
- IUPAC Name:
- (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Limit test:
- yes
- Total exposure duration:
- 48 h
Results and discussion
Applicant's summary and conclusion
- Executive summary:
The toxicity of the test substance was studied in an acute test on Daphnia magna in a limit test according to OECD 202. The organisms were exposed to a saturated solution of hydroxyprogesteronacetate over 48 hours. No adverse effects were observed. The EC50 ws higher than a saturated solution (Schering AG, 22 Feb 1995).
The study was conducted under GLP.
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