Registration Dossier
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EC number: 231-293-5 | CAS number: 7486-38-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Based on the absence of data on ready biodegradability, a read-across approach with adipic acid is applied.
Adipic acid is readily biodegradable as well as inherently biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
For disodium adipate no data on ready biodegradability are
available. Therefore, data of the corresponding acid are taken into
account for assessment and a read-across approach is applied, based on
the following justification. In aqueous media, disodium adipate and
adipic acid acid dissociate into the corresponding anion (1,6-hexandioic
acid ion) and the sodium ion and hydrogen ion (proton), respectively.
Fate, behavior and the ecotoxicological properties of adipic acid and
its disodium salt are thought to be an effect of the di-carboxylate ion
rather than of the sodium ion or the hydrogen ion (proton), which are
normal constituents in environmental systems and have no relevant
ecotoxic properties in low concentrations.
Therefore a read-across between disodium adipate and adipic acid is
justified
Several screening tests on biodegradation in water are available resulting in ready biodegradability of the substance.
In a test on ready biodegradability of adipic acid conducted according to the OECD guideline 301 D (Determination of the Ready biodegradability: Closed Bottle Test) 83 % degradation was observed after 30 days. Although, no information on the 10-day window criterion is given, and more than 70% of the test substance has been degraded indicating a potential for complete ultimate biodegradation, it is considered that the criteria for ready biodegradability are fulfilled. Based on this result the substance should be classified as readily biodegradable. The result is supported by an aerobic ready test, performed according to the national Japanese standard method comparable to the OECD TG 301 C guideline. After a period of 14 days more than 90% degradation of adipic acid was observed.
The inherent biodegradability of adipic acid was assessed according to the EU Method C.9 (Biodegradation: Zahn-Wellens Test), showing more than 90% degradation after 5 days. Based on these results the subtsance is considered to be inherently biodegradable.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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