Registration Dossier
Registration Dossier
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EC number: 428-410-9 | CAS number: 67014-36-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
The influence of the test substance on the respiration rate of activated sludge was investigated after a contact time of 30 minutes. The study procedure was based on OECD Guideline No 209. A stock solution of 0.5 g/L was prepared in Milli-Q water. 100 mg/L, corresponding to 100 mL of the prepared stock solution in 500 mL final volume, was tested in duplicate. No significant inhibition in respiration rate of the sludge was recorded at 100 mg/L. The duplicate measurement confirmed the result of the first measurement. Therefore no further testing was needed.
The respiration rates of the controls were within 15% of each other. The EC50 of the reference substance, 3,5-dichlorophenol, was 8 mg/L. Therefore, the test was considered to be valid.
In conclusion, under the conditions of this present test, the test substance was not toxic to waste-water bacteria at a concentration of 100 mg/L. (NOTOX B.V., 1998)
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