Registration Dossier
Registration Dossier
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EC number: 428-410-9 | CAS number: 67014-36-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The test substance is acutely toxic for aquatic invertebrates.
Key value for chemical safety assessment
Additional information
The test substance was assessed in a short term toxicity study to Daphnia magna according to OECD 202 and EU method C.2. Results of a range-finding test showed that the 48h-EC50 was between 1.0 and 10 mg/L with 100% immobility at 10 mg/L. The project was continued with an EC50 test exposing daphnids to a range of 1.0 to 10 mg/L. In contrast to the range-finding test, the final percentage of immobility was 65% at 10 mg/L. Hence, a final test was performed with concentrations of 0 (control), 1.8, 3.2, 5.6, 10, 18 and 32 mg/L, increasing by a factor of 1.8. All EC50 tests were performed with 10 daphnids per vessel. Analysis of the samples taken during the final test showed that the measured concentrations were in agreement with nominal. the test substance did not induce acute immobilization of Daphnia magna at 1.8 mg/L after 48 hours of exposure (NOEC). The 48h-EC50 was 2.9 mg/L (95% confidence interval between 2.7 and 3.3 mg/L). (NOTOX B.V., 1998)
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