4-(trifluoromethoxy)aniline

Guidance on Safe Use

First-aid measures

General advice: Show this safety data sheet to the doctor in attendance.

Inhalation: Move the victim to fresh air and keep at rest. Call a physician or poison control center immediately. Oxygen or artificial respiration if needed.

Skin contact: Wash off thoroughly with plenty of soap and water, if available with polyethyleneglycol 400, subsequently rinse with water. Call a physician or poison control center immediately.

Eye contact: In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.

Ingestion: Rinse mouth. Call a physician or poison control center immediately. If conscious give immediately one glass of water to drink. Ingest activated charcoal.

 

Most important symptoms and effects, both acute and delayed

Symptoms: Methaemoglobinemia

Fire-fighting measures

Suitable: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture:

Hazardous decomposition products due to incomplete combustion, In the event of fire the following may be released: Hydrogen fluoride, Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2)

 

Advice for firefighters

Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.

Further information: Evacuate personnel to safe areas. Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Cool closed containers exposed to fire with water spray.

Accidental release measures

Precautions: Keep unauthorized people away. Avoid contact with spilled product or contaminated surfaces. Use personal protective equipment.

Environmental precautions: Do not allow to get into surface water, drains and ground water.

Methods for cleaning up: Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Keep in suitable, closed containers for disposal.

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

 

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

Advice on safe handling: Use only in area provided with appropriate exhaust ventilation. Ensure adequate ventilation. Avoid contact with skin, eyes and clothing.

Advice on protection against fire and explosion: Keep away from heat and sources of ignition. Take measures to prevent the build up of electrostatic charge.

Requirements for storage areas and containers: Store in original container. Keep containers tightly closed in a dry, cool and well-ventilated place. Store in a place accessible by authorized persons only.

Advice on common storage: Keep away from food, drink and animal feedingstuffs.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

2810

Shipping information

Proper shipping name and description:

TOXIC LIQUID, ORGANIC, N.O.S.

Chemical name:

4-trifluoromethoxyaniline

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group I: Substances presenting high danger

Labels:

Packaging: 6.1, Bulk: 6.1, Haz ID: 66, EAC: 2X, EHS

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

2810

Shipping information

Proper shipping name and description:

TOXIC LIQUID, ORGANIC, N.O.S. (4-TRIFLUORMETHOXYANILINE)

Chemical name:

4-trifluoromethoxyaniline

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group I: Substances presenting high danger

Labels:

Packaging: 6.1, Bulk: 6.1, Haz ID: 66, EHS

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

2810

Shipping information

Proper shipping name and description:

TOXIC LIQUID, ORGANIC, N.O.S.

Chemical name:

4-trifluoromethoxyaniline

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group I: Substances presenting high danger

EmS code:

F-A

S-A

Labels:

Packaging: 6.1, Bulk: 6.1

Marine pollutant

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

2810

Shipping information

Proper shipping name and description:

TOXIC LIQUID, ORGANIC, N.O.S.

Chemical name:

4-trifluoromethoxyaniline

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group I: Substances presenting high danger

Labels:

6.1

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.

 

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

Respiratory protection: Suitable respiratory equipment: Multi-purpose filter ABEK

Hand protection: Nitrile rubber gloves, Directive Protective gloves complying with EN 374.

Eye protection: Tightly fitting safety goggles

Skin and body protection: Use suitable protective clothing, gloves and footwear, selected with regard to use conditions and exposure potential.

General protective measures: Use only in area provided with appropriate exhaust ventilation. Avoid contact with skin and eyes. Do not inhale vapours.

Stability and reactivity

Reactivity: Stable under normal conditions.

Thermal decomposition: To avoid thermal decomposition, do not overheat.

Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use.

Conditions to avoid: Heat, flames and sparks. Extremes of temperature and direct sunlight. Store only in orginal container.

Hazardous decomposition products: Can be released in case of fire: Carbon monoxide, Carbon dioxide (CO2), Nitrogen oxides (NOx), Hydrogen fluoride

Disposal considerations

During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.

Dispose in accordance with current regulations and, if necessary, after consultation with the site operator and/or with the responsible authority, the product may be taken to a waste disposal site or incineration plant.