Registration Dossier
Registration Dossier
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EC number: 240-383-3 | CAS number: 16291-96-6 An amorphous form of carbon produced by partially burning or oxidizing wood or other organic matter.
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 50 mg/kg bw/day
- Species:
- other: human
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Additional information
There is no evidence that charcoal or activated charcoal is orally toxic under repeat dose circumstances in humans where it is used for medical reasons. In fact all evidence suggests that it is beneficial in certain circumstances as a treatment for removing toxins from the stomach and gastric tract and for various other ailments.
Justification for selection of repeated dose toxicity inhalation - local effects endpoint:
Substance is a solid insoluble mainly inorganic powder. Dermal penetration is not a relevant route of exposure. Recently there are a large number of skin products appearing on the market that use activated charcoal as an ingredient in body scrubs, soaps and face masks which are designed to remove toxins and oils from the skin. It is unlikely that ingredients used in the personal care market have not been sanctioned for use in such applications and found to be harmless.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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