Registration Dossier
Registration Dossier
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EC number: 240-383-3 | CAS number: 16291-96-6 An amorphous form of carbon produced by partially burning or oxidizing wood or other organic matter.
Endpoint summary
Administrative data
Description of key information
ORAL - Ingestion of charcoal is not an expected route of exposure in normal use especially when in lump or granular form. However, charcoal has been used extensively in medicine for a significant length of time and is considered harmless for consumption. This end-point has been waived based on published medical evidence.
INHALATION - A single 4-h nose-only exposure to charcoal in rats followed by a 14-day observation period at a dose level 5 mg/L was not associated with mortality or any test item-related toxicological findings on the male and female animals. Accordingly, the acute inhalation median lethal concentration (4-h LC50) of charcoal rats was therefore considered to be greater than 4.97 mg/L.
DERMAL - Charcoal dust is essentially carbon. Elemental carbon in both amorphous and crystalline forms are known to be inert and generally non-toxic. Charcoal has been used in face scrubs and soaps to reduce the level of oils and toxins in the skin. This end point has been waived based on elemental and published data.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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