Vanadium oxysulphate

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Study period:

72 hours

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Justification for type of information:

Peer reviewed publication cited in government reviews

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

GLP compliance:

not specified

Specific details on test material used for the study:

Not specified.
Considered a good source of water soluble vanadium for aquatic testing.

Analytical monitoring:

yes

Details on sampling:

Samples for vanadium analysis were also collected at the start and end of each test to quantify actual exposure concentrations.

Vehicle:

no

Test organisms (species):

Scenedesmus quadricauda

Details on test organisms:

Scenedesmus quadricauda was identified as a regionally-representative green algal species

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

72 h

Hardness:

ca 110 mg/l CaCO3

Test temperature:

ca 23 C

pH:

ca 8.6

Details on test conditions:

Reconstituted water in continuous lighting

Reference substance (positive control):

no

Duration:

72 h

Dose descriptor:

IC50

Effect conc.:

ca. 4.12 mg/L

Nominal / measured:

meas. (arithm. mean)

Conc. based on:

element

Remarks:

Vanadium

Basis for effect:

growth rate

Key result

Duration:

72 h

Dose descriptor:

IC50

Effect conc.:

ca. 14 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

growth rate

Remarks on result:

other: Starting with IC50 4.12 mg/l for V and using molecular weight of constituent with greatest proportion of vanadium

Details on results:

The reported IC50 (growth rate) was in the range of 3.06 - 4.85 mg/l, with an EC10 of 0.27 mg/l vanadium, suggesting a shallow dose response.
Vanadium is considered to be an essential element for plants.

Conclusions:

Using a molecular weight of 173 for the registered substance, the IC50 has been estimated to be > 10 mg/l

Description of key information

Using a molecular weight of 173 for the registered substance, the IC50 has been estimated to be ca 14 mg/l

Key value for chemical safety assessment

EC50 for freshwater algae:

14 mg/L