Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013-01-22 to 2013-02-07
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. Substance ID is adequately specified with purity. Therefore full validation applies.
according to guideline
OECD Guideline 104 (Vapour Pressure Curve)
according to guideline
EU Method A.4 (Vapour Pressure)
GLP compliance:
yes (incl. QA statement)
inspection 10/07/2012, signature 30/11/2012
Type of method:
gas saturation method
Specific details on test material used for the study:
Storage conditions: room temperature in the dark
Key result
25 °C
Vapour pressure:
0.249 Pa

Average of vapour pressure (mean of three determinations (three flow rates)):

0.416 Pa at 30°C

1.06 Pa at 40°C

2.68 Pa at 50°C

Detailed data, the vapour pressure curve and the regression parameters are provided in the experimental report.



The linearity of the detector response with respect to concentration was assessed over the concentration range of 2.92 to 29.2 mg/L (n=5). This was satisfactory with a correlation coefficient of 1.000 being obtained.

Concentrations of sample solutions from traps 1 range between 12 and 44 mg/L (no substance detected in traps 2); some are slightly above the calibration range , however, regarding the low standard deviations obtained with the different flows, inaccuracy is considered negligible.



To ensure saturation control, three different flow rates were used at each temperature. From the data, it can be clearly seen that higher flow rates did not lead to lower vapor pressures, which means that the nitrogen was saturated with test item under the conditions of the test.

Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
Executive summary:

The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, gas saturation method.

Determinations were conducted at 30, 40 and 50°C, with three flow rates per temperature. Mass of evaporated test item was quantified by GC.

Vapour pressure at 25°C was extrapolated to be 0.249 Pa from the regression.

Description of key information

Closely extrapolated result from experimental measurements.
Low volatility.

Key value for chemical safety assessment

Vapour pressure:
0.249 Pa
at the temperature of:
25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study. The result is retained as key data.