Registration Dossier
Registration Dossier
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EC number: 907-498-7 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 Mar 2015 - 13 Mar 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 850.1010 (Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids)
- Version / remarks:
- 5th Ed. EPA-821-R-02-012
- Deviations:
- no
- GLP compliance:
- not specified
- Remarks:
- Accredited under ISO 17025
- Specific details on test material used for the study:
- Batch #148-116
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- TS not soluble in water. Afine suspension was generated by stirring and sonication.
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 141-152 mg CaCO3/L
- Test temperature:
- 19.0-21.0 °C
- pH:
- 7.42 - 8.15
- Dissolved oxygen:
- 7.5 - 8.3 ppm
- Conductivity:
- 486 - 490 µS/cm
- Nominal and measured concentrations:
- Nominal: 50, 100, 200, 400, 800 mg/L
- Details on test conditions:
- TEST SYSTEM
- Volume: ~0.040 L
- No. of organisms per vessel: 20
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4 - Reference substance (positive control):
- yes
- Remarks:
- NaCl
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 96.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Results with reference substance (positive control):
- 48-hr LC50 (NaCl): 5584 mg/L; 95% CL: 5279-5905 mg/L
- Reported statistics and error estimates:
- 95%-CI: 78.8-118 mg/L
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 48-h LC50 of E1218 against D.magna is 96.6 mg/L (nominal).
Reference
Description of key information
The 48-h LC50 of E1218 against D.magna is 96.6 mg/L (nominal).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 96.6 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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