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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
sodium;2-hexadecylsulfanyl-1H-benzimidazole-5-sulfonate
EC Number:
616-081-6
Cas Number:
743423-33-8
Molecular formula:
C23 H37 N2 Na O3 S2
IUPAC Name:
sodium;2-hexadecylsulfanyl-1H-benzimidazole-5-sulfonate
Test material form:
solid: particulate/powder

Results and discussion

Mass median aerodynamic diameter:
418.348 µm
Particle sizeopen allclose all
Percentile:
D10
Mean:
4.599 µm
St. dev.:
0.112
Percentile:
D50
Mean:
368.335 µm
St. dev.:
7.53
Percentile:
D90
Mean:
717.763 µm
St. dev.:
17.143

Applicant's summary and conclusion

Conclusions:
The results of the laser diffraction test conducted to determine the particle size of v182675 are summarised in the table below. The analysis was conducted on the fraction of the sample which was < 1000 μm using the small volume (wet) module (SVM) with acetonitrile as the dispersant.

Particle Size Analysis using small volume module (SVM) Average (μm)
Volume weighted mean 356.153
Median 368.335
Mode 492.842
MMAD (mass median aerodynamic diameter) 418.348
d10 - 10 % of material is < 4.599
d50 - 50 % of material is < 368.335
d90 - 90 % of material is < 717.763
volume of sample < 10.00 μm 19.14%