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Environmental fate & pathways

Biodegradation in water: screening tests

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Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1977
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
No information given on negative control and validity criteria.
Qualifier:
according to guideline
Guideline:
other: Modified OECD Confirmatory Tests
Version / remarks:
The test was conducted according to SOP A-12 (1974-09-01).
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, industrial (adaptation not specified)
Duration of test (contact time):
31 d
Initial conc.:
20 mg/L
Based on:
TOC
Initial conc.:
58 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
TOC removal
Details on study design:
TEST CONDITIONS
- Composition of medium: TOC content of medium: 107 mg/L

TEST SYSTEM
- Number of culture flasks/concentration: 1


CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
Key result
Parameter:
% degradation (TOC removal)
Value:
98
St. dev.:
4
Sampling time:
21 d
Parameter:
BOD5
Value:
175 mg O2/g test mat.
Remarks on result:
other: Test item conc. 20 mg/L
Parameter:
COD
Value:
874 mg O2/g test mat.
Remarks on result:
other: Test item conc. 10 mg/L
Validity criteria fulfilled:
not specified
Interpretation of results:
inherently biodegradable
Conclusions:
The substance was found to be inherently biodegradable (98% after 21 d based on TOC removal).
Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1978
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
No information given on negative control and validity criteria.
Qualifier:
according to guideline
Guideline:
other: Modified OECD Confirmatory Tests
Version / remarks:
The test was conducted according to SOP A-12 (1974-09-01).
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, industrial (adaptation not specified)
Duration of test (contact time):
21 d
Initial conc.:
20 mg/L
Based on:
TOC
Initial conc.:
57.9 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
TOC removal
Details on study design:
TEST CONDITIONS
- Composition of medium: TOC content of medium: 110 mg/L

TEST SYSTEM
- Number of culture flasks/concentration: 1


CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
Key result
Parameter:
% degradation (TOC removal)
Value:
84
St. dev.:
3
Sampling time:
21 d
Parameter:
BOD5
Value:
35 mg O2/g test mat.
Remarks on result:
other: Test item conc. 100 mg/L
Parameter:
COD
Value:
1 759 mg O2/g test mat.
Remarks on result:
other: Test item conc. 5 mg/L
Validity criteria fulfilled:
not specified
Interpretation of results:
inherently biodegradable
Conclusions:
The substance was found to be inherently biodegradable (84% after 21 d based on TOC removal).
Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1979
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
No information given on negative control and validity criteria.
Qualifier:
according to guideline
Guideline:
other: Modified OECD Confirmatory Tests
Version / remarks:
The test was conducted according to SOP A-12 (1974-09-01).
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, industrial (adaptation not specified)
Duration of test (contact time):
39 d
Initial conc.:
20 mg/L
Based on:
TOC
Initial conc.:
59.7 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
TOC removal
Details on study design:
TEST CONDITIONS
- Composition of medium: TOC content of medium: 118 mg/L

TEST SYSTEM
- Number of culture flasks/concentration: 1


CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
Key result
Parameter:
% degradation (TOC removal)
Value:
91
St. dev.:
6
Sampling time:
21 d
Parameter:
BOD5
Value:
150 mg O2/g test mat.
Remarks on result:
other: Test item conc. 20 mg/L
Parameter:
COD
Value:
1 008 mg O2/g test mat.
Remarks on result:
other: Test item conc. 10 mg/L
Validity criteria fulfilled:
not specified
Interpretation of results:
inherently biodegradable
Conclusions:
The substance was found to be inherently biodegradable (91% after 21 d based on TOC removal).
Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1989
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Remarks:
Test procedure not well documented
Qualifier:
according to guideline
Guideline:
OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
Version / remarks:
1981
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
- Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): ARA Birsfelden
Duration of test (contact time):
28 d
Initial conc.:
30 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Details on study design:
ThOD (test substance): 2.6 mg O2 / mg substance
Reference substance:
aniline
Key result
Parameter:
% degradation (O2 consumption)
Value:
0
St. dev.:
0
Sampling time:
26 d
Details on results:
The toxicity control did not indicate any inhibitory effect on activated sluge. The degradation rate was determined at 109% after 26 d based on O2 consumption.
Parameter:
BOD5
Value:
< 1 mg O2/g test mat.
Parameter:
COD
Value:
859 mg O2/g test mat.
Results with reference substance:
82% degradation after 26 d based on O2 consumption
Validity criteria fulfilled:
not specified
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
There was no biodegradation observed in an OECD 302C inherent biodegradabality test (0% after 26 d based on O2 consumption). The test substance is not considered to be inherently biodegradable.

Description of key information

Based on a weight-of-evidence approach with structural analogues it can be assumed that the target substance is inherently but not readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
inherently biodegradable

Additional information