Reaction products of 1,6-diisocyanatohexane, oligomers with 2-[(2-methacryloyl)oxy]ethyl 6-hydoxyhexanoate and 2-hydroxyethyl methacrylate

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14 Jan 2010

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

Study was performed carefully in accordance with an established OECD test guideline and with GLP criteria. Some volatile components may have lost, but the study adequately addresses the vapour pressure of the oligomeric components of the UVCB material.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: EEC Directive 92/69 A.4, Vapour pressure, Part: 1.4.6. Gas saturation method. Council Regulation (EC) No. 761/2009, 23 July 2009, Part A.4 "Vapour pressure"

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

static method

Test material

Reference

Name:

Unnamed

Type:

Constituent

Type:

Constituent

Details on test material:

- Name of test material (as cited in study report): MTDID 8191
- Substance type: UVCB material
- Physical state: Yellowish viscous liquid
- Concentration of oligomers: ≥99.0%
- Purity test date: 21 January 2010
- Lot/batch no.: MK 12/048
- Expiration date of the lot/batch: 27-Jan-2010
- Stability under test conditions: Not reported
- Storage condition of test material: In the refrigerator at about 5 °C

Results and discussion

Vapour pressure

Temp.:

25 °C

Vapour pressure:

2 420 Pa

Remarks on result:

other: Average of regression values for three runs.

Transition / decomposition

Transition / decomposition:

no

Any other information on results incl. tables

Table 1, Individual and mean interpolated vapour pressures at 25 °C for the test substance
Measurement	Calculated Vapor Pressure at 25 °C (Pa)
1	3.12 x 10^+3
2	2.29 x 10^+3
3	1.86 x 10^+3
Mean Value	2.42 x 10^+3
Standard Deviation	6.37 x 10^+2
Relative Std. Dev.	26.29%

Table 2, Measured vapour pressure v. temperature in three individual trials
Temperature	Pressure measured (mbar=hPa)
(°C)	1st Measurement	2nd Measurement	3rd Measurement
0.0	20	12	12
5.0	22	13	13
10.0	24	15	15
15.0	26	18	17
20.0	28	20	18
25.0	30	23	18
30.0	34	28	18
35.0	39	33	19
40.0	42	38	21
45.0	44	40	22
50.0	46	42	25
55.0	51	44	34
60.0	53	46	39
65.0	54	48	42
70.0	57	50	44
75.0	59	53	45
80.0	61	56	47
85.0	63	59	49
90.0	66	63	52
95.0	69	67	55
100.0	72	72	58
105.0	76	78	61
110.0	80	85	66
115.0	83	92	70
120.0	88	98	75
125.0	93	106	80
130.0	100	120	86
135.0	109	132	94
140.0	122	162	100

Interpolation of the VP of the test substances, exp 1 --> SEE ATTACHMENT 1 = FIG 1

Regression equation: lnVP (mbar) = 7.89 - 1326.45 * 1/T(K), R-sq = 0.9890

Interpolation of the VP of the test substances, exp 2 --> SEE ATTACHMENT 2 = FIG 2

Regression equation: lnVP (mbar) = 9.34 - 1850.50 * 1/T(K), R-sq = 0.9787

Interpolation of the VP of the test substances, exp 3 --> SEE ATTACHMENT 3 = FIG 3

Regression equation: lnVP (mbar) = 8.72 - 1726.03 * 1/T(K), R-sq = 0.9804

Low temperature readings were repeated as a check. These values did not coincide with the curve obtained for increasing temperature. This is most probably due to the composition of the test item. The test item might contain low boiling compounds, which have been released during heating.

It is not clear from the study report whether the low temperature readings are part of the repeated measurements or were recorded but not included in the study report. The fact that vapour pressure measurements were taken at low temperatures without heating is mentioned, but these values are also not included in the report. Test guideline OECD104 states that the static method is appropriate for multicomponent substances, but cautions that degassing should be at a temperature low enough to ensure that the composition of the material is not altered. The suggested loss of volatile components argues against the appropriateness of degassing. However, the test provides an adequate assessment of oligomeric materials within the test substance.

Applicant's summary and conclusion

Conclusions:

The vapour pressure of the test substance at 25°C is 2.42E+03 Pa.

Executive summary:

Vapour pressure of the test substance (CAS# 1101874-33-2) was measured using the static method according to OECD TG104. This method is suitable for substances and multicomponent liquids and solids in the range from 10 to 100,000 Pa. Vapour pressures as a function of temperature were transformed and analyzed according to the Clausius-Clapeyron equation. The interpolated vapour pressures at 25°C decreased during repeated runs, probably due to loss of volatiles from the test substance. The average of the three runs was reported. as the vapour pressure at 25°C. The vapour pressure of the test substance at 25°C is 2.42E+03 Pa. The test was conducted according to internationally-accepted test guidelines and GLP standards. Some volatile components were evidently lost during the procedure, but the study addresses the vapour pressure of the oligomeric components of the UVCB material. Therefore, this study is classified as reliable with restrictions.