Registration Dossier
Registration Dossier
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EC number: 211-976-4 | CAS number: 728-88-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- secondary source
- Title:
- LD50 acute oral toxicity
- Author:
- Oyo Yakuri
- Year:
- 1 971
- Bibliographic source:
- Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 5,421
Materials and methods
Test material
- Reference substance name:
- Tolperisone
- EC Number:
- 211-976-4
- EC Name:
- Tolperisone
- Cas Number:
- 728-88-1
- Molecular formula:
- C16H23NO
- IUPAC Name:
- 2-methyl-1-(4-methylphenyl)-3-(piperidin-1-yl)propan-1-one
Constituent 1
Test animals
- Species:
- rat
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 450 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
