Registration Dossier
Registration Dossier
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EC number: 214-507-1 | CAS number: 1137-42-4
Endpoint summary
Administrative data
Description of key information
QSAR prediction with OASIS TIMES: not sensitizing. The calculated value was out of domain (structural fragment) and is therefore only a hint (see the attachement for detailed information).
Read-across data captured from published Benzophenone registration dossier:
Skin guinea pigs (OECD Guideline 406): not sensitizing (Sharp et al., 1978, Toxicology 9, 261-271)
Skin guinea pigs (OECD Guideline 406): not sensitizing (Calas et al., 1977, Contact Dermatitis 3, 186-194)
Skin Maximization test in human volunteers: not sensitizing (Opdyke et al., 1979, Food Cosmet Toxicol 11, 873-874)
Key value for chemical safety assessment
Justification for classification or non-classification
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available read-across data is reliable and suitable for classification purposes under Regulation (EC) No 1272/2008, as amended for the seventh time in Regulation (EC) No 2015/1221. As a result the substance is considered to be not classified as sensitising to the skin.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
