Alcohols, C12-14

Toxicity to terrestrial arthropods

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

toxicity to terrestrial arthropods: long-term

Data waiving:

other justification

Justification for data waiving:

other:

Reference 2

Endpoint:

toxicity to terrestrial arthropods: short-term

Type of information:

other: published data

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Qualifier:

no guideline available

GLP compliance:

no

Application method:

spray

Analytical monitoring:

not specified

Vehicle:

no

Test organisms (species):

Apis mellifera

Animal group:

Hymenoptera (honeybees)

Study type:

field study

Limit test:

no

Total exposure duration:

1 h

Reference substance (positive control):

not specified

Duration:

1 h

Dose descriptor:

other: NOEL

Effect conc.:

6.6 other: ml/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: Chemical avoidance

Duration:

4 h

Dose descriptor:

other: NOEL

Effect conc.:

6.6 other: ml/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: Chemical avoidance

Duration:

1 h

Dose descriptor:

other: NOEL

Effect conc.:

30 other: ml/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: Chemical avoidance

Duration:

1 h

Dose descriptor:

other: NOEL

Effect conc.:

6 600 mg/kg soil dw

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: Chemical avoidance

A study of NC-NC Not Coded duration using no substrate media was conducted in a FieldN site location with Not Coded obtained Apis mellifera (Honey Bee). The organism(s) (age: NR NR and organism characteristics of: NR) were exposed for a duration of 1 hour(s) to a(n) 1 dosed x time(s) per study period application of 1-Hexanol (CAS # 111273) in NR carrier or a(n) NR positive control through a(n) hand spray exposure route. The reported chemical concentrations are the result of unmeasured analysis of chemical solutions and are based on the NR ion. (Reference 81711, Mayer, D.F., J.D. Lunden, G. Kovacs, and E.R. Miliczky, 2001, Test Number 570952).

Conclusions:

Substance appears to have no significant adverse effect on bees

Description of key information

Substance (read across) appears to have no significant adverse effect on bees.
There are no data on the toxicity of alcohols to soil dwelling organisms. The significance of this lack of data may need to be considered , since Level III results indicate that if released to air, or directly to soil, e.g. via spreading of WWTP sludge, a significant proportion of longer chain alcohols would be expected to arise in the terrestrial compartment. However, the absolute quantity is expected to be small, and rapid degradation is anticipated, particularly in view of the rapid degradation seen in studies using soils.

Key value for chemical safety assessment

Short-term EC50 or LC50 for soil dwelling arthropods:

33 000 mg/kg soil dw

Long-term EC10, LC10 or NOEC for soil dwelling arthropods:

6 600 mg/kg soil dw

Additional information

Substance (read across) appears to have no significant adverse effect on bees.

There are no data on the toxicity of alcohols to soil dwelling organisms. The significance of this lack of data may need to be considered , since Level III results indicate that if released to air, or directly to soil, e.g. via spreading of WWTP sludge, a significant proportion of longer chain alcohols would be expected to arise in the terrestrial compartment. However, the absolute quantity is expected to be small, and rapid degradation is anticipated, particularly in view of the rapid degradation seen in studies using soils.