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EC number: 259-915-0 | CAS number: 55947-46-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
96 hrs aquatic toxicity study (EPI suite, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt (CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on algae in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be 322000 mg/l. Based on the result the chemical was considered as not classified to toxicity to algae according to the CLP regulations.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 322 000 mg/L
Additional information
Various predicted studies for the target chemical 2-Propyne-1-sulfonic acid, sodium salt and read across study were reviewed to summarize the following information:
96 hrs aquatic toxicity study (EPI suite, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt (CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on algae in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be 322000 mg/l. Based on the result the chemical was considered as not classified to toxicity to algae according to the CLP regulations.
76 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt(CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on the algae in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be49.998950958 mg/Lon the basis of growth rate. As the log Kow for the chemical was -2.17, on the basis of this the chemical was considered as not classified for toxicity to algae as per CLP regulations.
Toxicity to algae (Scenedesmus subspicatus) was determined ( IUCLID datset (EUROPEAN COMMISSION European Chemicals Bureau,2000 )) using Algal inhibition test (GLP Lab) for 72 hrs. After experiment the toxicity to algae EC50 value and NOEC value were determined to be >1000 and >=1000 mg/l for 2-Propyne-1-sulfonic acid, sodium salt on the basis of growth rate.
On the basis of results of various predictions and read across study, the chemical2-Propyne-1-sulfonic acid, sodium salt can be considered as not likely to be toxic to algae at environmentally relevant concentrations and can be classified as non- hazardous as per the criteria of CLP regulation
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