Registration Dossier
Registration Dossier
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EC number: 232-102-8 | CAS number: 7786-67-6
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Isopulegol
- EC Number:
- 201-940-6
- EC Name:
- Isopulegol
- Cas Number:
- 89-79-2
- IUPAC Name:
- 2-isopropenyl-5-methylcyclohexanol
- Reference substance name:
- 5-methyl-2-(1-methylvinyl)cyclohexan-1-ol
- EC Number:
- 232-102-8
- EC Name:
- 5-methyl-2-(1-methylvinyl)cyclohexan-1-ol
- Cas Number:
- 7786-67-6
- Molecular formula:
- C10H18O
- IUPAC Name:
- 5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol
- Details on test material:
- Name of test material: L-Isopulegol
Constituent 1
Constituent 2
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Strauss 1820
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 20.1 - 20.5 °C
- pH:
- 7.5 - 8.5
- Dissolved oxygen:
- Must remain ≥ 3mg/L
- Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 53.2 mg/L
- Nominal / measured:
- nominal
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 46 mg/L
- Nominal / measured:
- nominal
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Results with reference substance (positive control):
- EC50 (24h) = 0.85 mg/L
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EC50(48h) is 53.2 mg/L
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