Oligomer of 4,4-bis(1,1,3,3-tetramethylbutyl)diphenylamine with N-(4-(2,4,4-trimethylpentan-2-yl)phenyl)naphthalen-1-amineor (according to REACH Guidance on substance identification)Reaction mass of N,N,N'-tri(4-(1,1,3,3-tetramethyl-butyl)phenyl-N'-(di(4-(1,1,3,3-tetramethylbutyl)phenyl)amino)-naphthylhydrazine, N,N,N'-tri(4-(1,1,3,3-tetramethyl-butyl)phenyl-N'-(bis-(di(4-(1,1,3,3-tetramethylbutyl)phenyl)amino))-naphthylhydrazine, N,N,N'-tri(4-(1,1,3,3-tetramethyl-butyl)phenyl-N'-(bis(N''-(4-(1,1,3,3-tetramethylbutyl)phenyl)amino)-N''-naphthyl)naphthylhydrazine, N,N,N'-tri(4-(1,1,3,3-tetramethyl-butyl)phenyl-N'-[x-(di-(4-(1,1,3,3-tetramethylbutyl)phenyl)amino-(4-(1,1,3,3-tetramethylbutyl)phenyl)-amino)naphthylamino)naphthyl-hydrazine, tetrakis 4-(1,1,3,3-tetra-Methyl-butyl)phenylhydrazine and N,N,N'-tris(4-(1,1,3,3-tetramethyl-butyl)phenyl-N'-naphthylhydrazine

Skin irritation / corrosion

Administrative data

Endpoint:

skin irritation: in vivo

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

other: Body responsible for the test

Title:

Unnamed

Year:

1995

Report date:

1995

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: Annex V

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

415-860-6

EC Name:

-

Cas Number:

68938-84-1

IUPAC Name:

1-(naphthalen-1-yl)-2,2-bis(4-octylphenyl)-1-[4-(2,4,4-trimethylpentan-2-yl)phenyl]hydrazine; 1-N-[2-({2-[bis(4-octylphenyl)amino]-4-octylphenyl}(4-octylphenyl)amino)-4-octylphenyl]-1-N-(4-octylphenyl)-4-N-[4-(2,4,4-trimethylpentan-2-yl)phenyl]naphthalene-1,4-diamine; 1-N-{2-[bis(4-octylphenyl)amino]-4-octylphenyl}-1-N-(4-octylphenyl)-4-N-[4-(2,4,4-trimethylpentan-2-yl)phenyl]naphthalene-1,4-diamine; 4-octyl-N-(4-octylphenyl)aniline; 5-[2,2-bis(4-octylphenyl)-1-[4-(2,4,4-trimethylpentan-2-yl)phenyl]hydrazin-1-yl]-1-N,1-N,3-N,3-N-tetrakis(4-octylphenyl)naphthalene-1,3-diamine; 5-[2,2-bis(4-octylphenyl)-1-[4-(2,4,4-trimethylpentan-2-yl)phenyl]hydrazin-1-yl]-N,N-bis(4-octylphenyl)naphthalen-2-amine; 5-octyl-1-N,1-N,2-N-tris(4-octylphenyl)benzene-1,2-diamine; tetrakis(4-octylphenyl)hydrazine

Test animals

Species:

other: Rabbit (New Zealand White)

Test system

Type of coverage:

semiocclusive

Vehicle:

other: applied with a patch moistened with water

Amount / concentration applied:

500 mg

Duration of treatment / exposure:

4 h

Number of animals:

6

Results and discussion

In vivo

Results

Results 1

Irritation parameter:

erythema score

Basis:

mean

Score:

0

Max. score:

0

Remarks on result:

other: Max. duration: 0 d; Max. value at end of observation period: 0

Results 2

Irritation parameter:

edema score

Basis:

mean

Score:

0

Max. score:

0

Remarks on result:

other: Max duration: 0d; Max. value at end of observation period: 0

Irritant / corrosive response data:

Reversibility of any observed effect: Changes fully reversible within 1 day.

Other effects:

Due to the colour of the test substance, there was a slight yellow staining of the treated area. This was not considered to have obscured any dermal effects.

Very slight erythema was observed in 1 animal at 55 minutes after treatment but was reversible and not observed at 24 hours after treatment.

Applicant's summary and conclusion

Interpretation of results:

other: not classified