3-aminophenol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

9 September 2013 to 10 December 2013

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Principles of method if other than guideline:

The boiling point of 3-aminophenol is determined.

GLP compliance:

no

Type of method:

method according to Siwoloboff

Remarks:

Capillary method

Specific details on test material used for the study:

- Name of test material: 3-aminophenol
- IUPAC name: 1-Hydroxy-3-amino-benzene
- Molecular weight: 109.127 g/mole
- Molecular formula: C6H7NO
- Smiles: c1c(cccc1O)N
- InChI: 1S/C6H7NO/c7-5-2-1-3-6(8)4-5/h1-4,8H,7H2
- Substance type: Organic
- Physical state: Solid Crystalline (white)

Key result

Boiling pt.:

284 °C

Atm. press.:

99 kPa

Decomposition:

no

Remarks on result:

other: (742.560 mmHg pressure)

The determination of the boiling point was performed by visual judgement using the capillary method. At about 280 °C in the preliminary test, the number of air bubbles increased. To confirm the result obtained in the preliminary test, the determination of the boiling point was performed three times, heating quickly up to 265 °C and afterwards slowly using a heating rate of 1 °C/min. A clear boiling point, as defined in the guideline with a current stream of bubbles evolving from the capillary, was observed at a heating temperature of 284 °C (558 K). The results were evaluated because they fulfill the criteria of repeatability.

Conclusions:

The test item 3-aminophenol started boiling at 284 °C (558 K) at ambient barometric pressure (99.0 kPa).

Executive summary:

The purpose of this study was to evaluate the boiling point of the test item by the capillary method using an electronic controlled heating system, according to the A2 method and the OECD 103 guideline, and following the GLP. The determination of the boiling point was performed by visual judgement using the capillary method. At about 280 °C in the preliminary test, the number of air bubbles increased. To confirm the result obtained in the preliminary test, the determination of the boiling point was performed three times, heat-ing quickly up to 265 °C and afterwards slowly using a heating rate of 1 °C/min. A clear boiling point, as defined in the guideline with a current stream of bubbles evolving from the capillary, was observed at a heating temperature of 284 °C (557 K). The results were evaluated because they fulfill the criteria of repeatability.

Description of key information

The test item 3-aminophenol started boiling at 284 °C (558 K) at ambient barometric pressure (99.0 kPa).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

284 °C

Additional information

The purpose of this study was to evaluate the boiling point of the test item by the capillary method using an electronic controlled heating system, according to the A2 method and the OECD 103 guideline, and following the GLP. The determination of the boiling point was performed by visual judgement using the capillary method. At about 280 °C in the preliminary test, the number of air bubbles increased. To confirm the result obtained in the preliminary test, the determination of the boiling point was performed three times, heat-ing quickly up to 265 °C and afterwards slowly using a heating rate of 1 °C/min. A clear boiling point, as defined in the guideline with a current stream of bubbles evolving from the capillary, was observed at a heating temperature of 284 °C (557 K). The results were evaluated because they fulfill the criteria of repeatability.