Registration Dossier
Registration Dossier
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EC number: 291-367-8 | CAS number: 90387-90-9
Endpoint summary
Administrative data
Description of key information
Additional information
Graphite, acid-treated is an inorganic solid, consisting of natural graphite and variable amounts of either intercalated nitric acid or acetic acid. The main component – graphite - is a naturally occurring inorganic solid substance which is insoluble in water. Due to its physico-chemical properties, i.e. absence of lipophilic functional groups which would enhance lipid (fat) solubilisation properties and therefore facilitate the uptake into the organism, graphite itself can be regarded as not bioaccumulative and harmless.
The intercalated nitric acid or acetic acid and the intercalated ions (nitrite/nitrate, acetate) are partially leached out by water. The aquatic harmlessness of graphite, acid-treated has been demonstrated by the negative testing results of the study on acute toxicity to fish (see section 6.1.1 of the IUCLID dossier) and the toxicity to freshwater green algae (see section 6.1.5 of the IUCLID dossier), resulting in the determination of the NOEC to be 100 mg/L.
The absence of cytotoxic effects, which have been revealed in an Ames-Test with several Salmonella typhimurium strains(see section 7.6.1 of the IUCLID dossier), underline furthermore that the substance is neither bioavailable nor that the concentrations of the leached out ions play a systemically and therefore toxicologically relevant role.
Production and use of graphite, acid-treated only take place at a small number of industrial sites with no relevant releases of this substance to waste water streams and with no probability of any significant release to the environment from products. Therefore, significant exposure of the aquatic compartment is unlikely. Even if accidental exposure of the aquatic compartment occurs, graphite, acid-treated does not pose any aquatoxic hazards due to the aforementioned arguments.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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