Registration Dossier
Registration Dossier
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EC number: 204-287-5 | CAS number: 118-92-3
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According OECD 107
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- not specified
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Anthranilic acid
- EC Number:
- 204-287-5
- EC Name:
- Anthranilic acid
- Cas Number:
- 118-92-3
- Molecular formula:
- C7H7NO2
- IUPAC Name:
- 2-aminobenzoic acid
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 0.99
- Temp.:
- 23 °C
- pH:
- ca. 3.7
- Remarks on result:
- other: pH derived from water solubility test
Any other information on results incl. tables
Table 1: Results in detail
no. |
stock solution [mL] |
n-octanol
[mL] |
conc. in n-octanol phase [mg/L] |
conc. in water phase [mg/L] |
Log Pow |
A1 |
5 |
10 |
315,6 |
47,9 |
0,82 |
A2 |
5 |
10 |
315,7 |
48,1 |
0,82 |
B1 |
10 |
10 |
597,5 |
57,2 |
1,02 |
B2 |
10 |
10 |
607,0 |
55,9 |
1,04 |
C1 |
20 |
10 |
1107,8 |
85,4 |
1,11 |
C2 |
20 |
10 |
1106,5 |
86,4 |
1,11 |
mean |
- |
- |
- |
- |
0,99 |
stock solution: 636 mg/L
Applicant's summary and conclusion
- Conclusions:
- Due to the partition coefficient n-octanol-water bioaccumulation is not expected.
- Executive summary:
The partition coefficient n-octanol/water of the test item is 0.99 determined according to OECD 107
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