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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December 09-12, 1986
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1987
Report date:
1987

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EPA primary dermal irritation in rabbits (40 CFR section 798.4470)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
419-690-3
EC Name:
-
Cas Number:
88020-55-7
Molecular formula:
[(C12H25)3NH]4Mo8O26
IUPAC Name:
tridodecylamine hydrate molybdenum

Test animals

Species:
rabbit
Strain:
other: New Zealander albino Rabbits

Test system

Type of coverage:
semiocclusive
Preparation of test site:
shaved
Vehicle:
other: None , a gauze patch wa placed and moistene with 0.5 ml of distilled water
Amount / concentration applied:
500 mg
Duration of treatment / exposure:
4 h
Observation period:
30-60 minutes after patch removal
24-48-72 hours after patch removal
Number of animals:
6 rabbits (young adults)

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
erythema score
Basis:
mean
Score:
0
Max. score:
0
Remarks on result:
other: Max. duration: 0 d; Max. value at end of observation period: 0
Irritation parameter:
edema score
Basis:
mean
Score:
0
Max. score:
0
Remarks on result:
other: Max. duration: 0 d; Max. value at end of observation period: 0
Other effects:
none

Any other information on results incl. tables

Overall results (showing mean scores if > 3 animals) : calculated on the basis of the scores for each animal at 24, 48 and 72 hours

Applicant's summary and conclusion

Interpretation of results:
other: not classified