Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 25th, 1996
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report Date:
1996

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Version / remarks:
December 1992
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
May 12th, 1981
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
< -2
Temp.:
20 °C
Remarks on result:
other: pH not mentioned

Any other information on results incl. tables

The saturation concentration of the substance in n-octanol was determined to be 3.3 mg/l in the preliminary test. The partition coefficient of the substance was estimated to be log Pow < -4.9 by calculation using the saturation concentration of the substance in pure solvents. However, the results obtained by the preliminary partitioning experiment has shown that the expected log Pow lies outside the range accessible by the flask shaking method. Therefore no further testing was performed. In conclusion, the partition coefficient of the substance was estimated to be log Pow =< -2 at 20 °C.

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test substance was estimated to be log Pow = < -2 at 20 °C.