Decene, hydroformylation products, low boiling

Short-term toxicity to fish

Description of key information

The short-term toxicity in fish of components of Alchisor TAL 111 has been documented within this dossier.  Adequate reliable measured data exists for short-term toxicity to fish to components of Alchisor TAL 111 (namely, C9 -C14 aliphatics (2 -25% aromatics)), but no studies are available for the analogue substance Alchisor TAL 123. In a conservative approach the most sensitive study result from across the constituent category has been identified and used to address the hazard endpoint in question. The most sensitive study result is a reliable study with C10-C13 hydrocarbon solvents (Shell, 1997) which reports an LL50 for short term toxicity in fish of 10 to 30 mg/l. Consequently this range of values will be taken as the short-term toxicity in fish endpoint for Alchisor TAL 111. 

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

10 mg/L

Additional information

Alchisor TAL 111 is decene, hydroformylation products, low boiling and can be characterised as a UVCB substance. As defined in the ‘Read-Across Justification Document’ section 13, data provided for the analogue substance Alchisor TAL 123 and the Alchisor TAL 111 consitutent category substances, Category 3 hydrocarbon solvents, are representative of Alchisor TAL 111 and suitable for assessment purposes. Study data for each analogue/constituent category has been evaluated and considered together. Two reliable (Klimisch 1) short-term toxicity studies in fish have been conducted for constituent categories of Alchisor TAL 111 (namely, C9 -C14 aliphatics (2 -25% aromatics)), although no studies are available for the analogue substance, Alchisor TAL 123, and are included in this dossier. In a conservative approach the most sensitive study result from across the constituent categories will be identified and used to address the hazard endpoint in question.

 

C9-C14 Aliphatics (2-25% Aromatics)

Two reliable (Klimisch 1 or 2) short-term toxicity studies for fish were available for C9-C14 aliphatics (2-25% aromatics) both of which are provided by Shell Research and Technology Centre. In the first the Shell Research and Technology Centre (1995) conducted a reliable (Klimisch 1) GLP compliant OECD 203 study with low aromatic white spirit (identified as hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%)). The 96 -hr LL50 for fish was 10 -100 mg/l (WAF; water accommodated fraction). In the second the Shell Research and Technology Centre (1997) conducted a reliable (Klimisch 1) GLP compliant OECD 203 study with low aromatic white spirit (identified as hydrocarbons, C10-C13, C8-C12 & C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%)). The 96 -hr LL50 for fish was 10 -30 mg/l (WAF), which is the most sensitive result from the two reliable short-term studies for C9-14 aliphatics (2-25% aromatics).

  

The short-term toxicity in fish of constituents of Alchisor TAL 111 has been documented within this dossier. Adequate reliable measured data exists for short-term toxicity to fish to components of Alchisor TAL 111 (namely, C9 -C14 aliphatics (2 -25% aromatics)). In a conservative approach the most sensitive study result from the constituent categories has been identified and used to address the hazard endpoint in question.The most sensitive study result has been identified as a reliable study with the C10 -C13 hydrocarbons (n'alkanes, isoalkanes, cyclics and aromatics (2 -25%) (Shell, 1997) which reports an LL50 for short term toxicity in fish of 10 -30 mg/L. Consequently this range of values will be taken as the short-term toxicity in fish endpoint for Alchisor TAL 111.