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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: The study was conducted in compliance with GLP standards. The study was carried out according to Guideline C.2. However, full study report is not available as the data is > 12 year old and summaries have been prepared using data provided by ECHA.

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1993

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
413-920-6
EC Name:
-
Cas Number:
88949-33-1
Molecular formula:
C30H20N2O2
IUPAC Name:
3,6-bis({[1,1'-biphenyl]-4-yl})-1H,2H,4H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione
Constituent 2
Reference substance name:
3,6- bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
IUPAC Name:
3,6- bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: Cremophor RH40, 100 mg/L

Test organisms

Test organisms (species):
Daphnia magna

Study design

Total exposure duration:
48 h

Test conditions

Hardness:
250 mg CaCO3/L

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Details on results:
%Concentration loss over test: 50

Applicant's summary and conclusion

Conclusions:
The study was conducted in compliance with GLP standards according to Guideline C.2. Cremophor RH40 was used as dispersant as the substance has low water solubility. The EC50 after 48 h was determined to be >100 mg/L.