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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer reviewed database

Data source

Reference
Reference Type:
publication
Title:
not given
Author:
Jacobson, Alan R.; Moe, Scott T.; Allen, P. D
Year:
2006
Bibliographic source:
Jacobson, Alan R.; Moe, Scott T.; Allen, P. D.; Fessenden, James D., Molecular Pharmacology, 70(1), <2006>, 259 - 266 as cited in REAXYS online query date 2014-02-21

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Secondary literature source no data about the method was available.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chlorophenol
EC Number:
203-402-6
EC Name:
4-chlorophenol
Cas Number:
106-48-9
Molecular formula:
C6H5ClO
IUPAC Name:
4-chlorophenol
Test material form:
solid: crystalline

Results and discussion

Dissociating properties:
yes
Dissociation constant
No.:
#1
pKa:
9.47
Remarks on result:
other: No information about the temperature was given

Applicant's summary and conclusion