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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Study period:
2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
GLP compliance:
yes (incl. QA statement)
Remarks:
see report
Test type:
fixed dose procedure
Limit test:
yes

Test material

Constituent 1
Reference substance name:
864970-33-2
Cas Number:
864970-33-2
IUPAC Name:
864970-33-2

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water

Results and discussion

Preliminary study:
No mortality at 2000 mg/kg b. w. either for males or for females.
Mortality:
No mortality
Clinical signs:
other: No signs of systemic toxicity
Gross pathology:
No abnormalities were noted at necropsy

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Conclusions:
The acute oral median lethal dose (LD50) of the organic part of PACTT, 2 Na in the female Sprague-Dawley CD strain rat was estimated to be greater than 2000 mg/kg body weight. As the mineral part of PACTT, 2 Na, Sodium Bromide is not either classified for acute oral toxicity, the multi constituent substance is not classified for acute oral toxicity according to GHS criteria.