Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

According to column 2 of REACH Annex VII, performing of an experimental study is not useful in case of hydrolytical instability. In this case a half-life of about 15 seconds was reported in a hydrolysis test. Nevertheless it was possible to achieve an experimental value of 4.51 for monomeric MDI. This component is a main component present in the substance.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

A calculated value of Pow = 7.74,  obtained using EPIWIN 4.00 with an idealised structure (one isocyanate group of 4,4-MDI is modified with 2-ethyl-hexanol). Both values, from monomeric MDI and for modified 2 -ethyl hexanol structure are due to the rapid hydrolysis only of theoretical interest.