Registration Dossier
Registration Dossier
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EC number: 423-340-5 | CAS number: 162881-26-7 CGI 819
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Test conducted according to Directive 87/302/EC and compliant with GLP.
Data source
Reference
- Reference Type:
- other: Body responsible fo the test
- Title:
- Unnamed
- Year:
- 1 997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 87/302/EC
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
- EC Number:
- 423-340-5
- EC Name:
- Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
- Cas Number:
- 162881-26-7
- Molecular formula:
- C26H27O3P
- IUPAC Name:
- [phenyl(2,4,6-trimethylbenzoyl)phosphoryl](2,4,6-trimethylphenyl)methanone
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test organisms
- Test organisms (species):
- activated sludge
Study design
- Test type:
- other: aerobic
- Total exposure duration:
- 3 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Details on results:
- The study examined the five nominal test concentration 6, 12, 24, 50 and 100 mg/L and three inoculum controls. An obvious excess of test substance was present at all nominal concentrations but the test substance was generally finely distributed. In comparison to the controls, the respiration rate of the activated sludge was practically not inhibited up to 100 mg/L nominal (or the limit of water solubility).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
