Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-552-5 | CAS number: 122-52-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
In a guinea pig maximization test (OECD TG 406, no GLP) with 5% intracutaneous induction and 100% epicutaneous induction and challenge, 19 out of 20 animals showed positive results at 48 hours after challenge with the undiluted test material. None of the negative control animals showed any positive effects. The test substance has shown to be a skin sensitizer.
Migrated from Short description of key information:
The test substance is sensitizing to the skin based on the data of a GPMT (OECD TG 406, no GLP).
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
There is no information available on the potential for the test substance to produce respiratory sensitization in animals or humans.
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
-Classification for sensitization is required: Xi, R43.
Classification, Labeling, and Packaging Regulation (EC) No. 1272/2008:
- The test substance has to be classified as a skin sensitizer of the category 1B.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
