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EC number: 231-441-9 | CAS number: 7550-45-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original reference in foreign language
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of titanium tetrachloride
- Author:
- Yang H; Zhang J, Feng S, Wang X, Chen Y, Liu Y
- Year:
- 1 997
- Bibliographic source:
- Weisheng Dulixue Zazhi 11(2): 131-133
Materials and methods
- Principles of method if other than guideline:
- Rats were exposed to the test substance, an oral LD50 value was determined
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Titanium tetrachloride
- EC Number:
- 231-441-9
- EC Name:
- Titanium tetrachloride
- Cas Number:
- 7550-45-0
- Molecular formula:
- Cl4Ti
- IUPAC Name:
- titanium tetrachloride
- Details on test material:
- unknown
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: unknown
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 180-220 g
ENVIRONMENTAL CONDITIONS
unknown
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- other: unknown
- Details on oral exposure:
- unknown
- Doses:
- unknown
- No. of animals per sex per dose:
- unknown
- Control animals:
- other: unknown
- Details on study design:
- unknown
- Statistics:
- unknown
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 586.76 mg/kg bw
- 95% CL:
- >= 510.15 - <= 678.87
- Mortality:
- unknown
- Clinical signs:
- unknown
- Body weight:
- unknown
- Gross pathology:
- unknown
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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