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EC number: 232-476-2 | CAS number: 8050-15-5
In an acute oral toxicity study, a group of five male rats was administered a single dose of Resin acids and Rosin acids, hydrogenated, Me esters by gavage at a dose level of 2000 mg/kg bw. Serving as controls, an additional group of five male rats was administered distilled water at 2.0 mL/kg bw. All rats were observed for mortality and adverse clinical signs for a period of 14 days. No mortality was noted in either treated or control animals. Immediately following dosing of the test substance, excitation and the appearance of piloerection were observed. These observations disappeared over the following hours. No abnormal clinical signs were recorded for control animals. Daily examinations for 14 days following treatment showed no changes in the state or behavior of the animals. All treated and control animals gained weight over the course of the study. At necropsy, no gross lesions were observed. The oral LD50 in male rats is considered to be greater than 2000 mg/kg bw. Based on the results of this study, Resin acids and Rosin acids, hydrogenated, Me esters is considered to be a low toxicity hazard upon ingestion.
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