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EC number: 263-061-4 | CAS number: 61789-45-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility
Key value for chemical safety assessment
Additional information
No study is available on short-term toxicity of fatty acids, dehydrated castor-oil (CAS 61789-45-5) to invertebrates.
Therefore ecotoxicological effects are predicted from adequate and reliable data for source substance(s) within the group by read-across to the target substances in the group applying the group concept in accordance with Annex XI, Item 1.5, of Regulation (EC) No 1907/2006.
The main constituents of the mixture are C18'' conjugated and C18''. Thus, read-across is performed to oleic acid C18' (CAS 112-80-1), which is also a member of the fatty acids category. Furthermore, supporting read across is performed to fatty acids, tall oil (CAS 61790 -12 -3), since the main components of this fatty acid mixture are also unsaturated C18 components (50-60% C18', 35-40% C18'') and to a mixture with linoleic acid C18'' (CAS 60 -33 -3) with the following constituents: 60% C18'', 25% C18' and minor amounts of C18''', C16, C14 and C18.
In the test available for oleic acid C18' daphnids (Daphnia magna) were exposed in a limit test under semi-static conditions. The study was provided by the Ministry of the Environment, Government of Japan (2003) and conducted as limit test according to OECD 202 under GLP conditions. The EC50 (48 h) was reported to be > 2.8 mg/L based on arithmetic mean measured concentration (corresponding to > 3.6 mg/L based on nominal concentration).
The study on acute toxicity to daphnids with fatty acids, tall oil was condcuted according to OECD 202 under GLP conditions (Pine Chemical Association, 2002). Daphnia magna was exposed to water accomodated fractions (WAF) of 1, 10, 100 and 1000 mg/L (nominal). Since no mortality was observed up to the highest loading rate an EL50(48h) of > 1000 mg/L was stated. Thus no effect up to the limit of water solubility could be detected.
A GLP guideline study on a mixture with linoleic acid (content 60%) was conducted by Özkabakcioglu (2000) with Daphnia magna acccording to OECD 202. Daphnids were exposed for 48 h in a static test to WAFs of the test item, since the test substance has a low water solubility (< 2.2 mg/L in the test medium). Results were based on nominal loading rates, no effects were observed up to a loading rate of 30 mg/L. In the highest loading rate of 100 mg/L 100% mortality was observed, probably due to physical effects caused by this loading rate far above the water solubility.
Taking into account the listed results no short-term effects on invertebrates of fatty acids, dehydrated castor-oil are expected up to the limit of water solubility.
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