Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
8.8 µg/L
Assessment factor:
50
PNEC freshwater (intermittent releases):
0.1 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.88 µg/L
Assessment factor:
500

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
100 mg/L
Assessment factor:
10

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.13 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.013 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.021 mg/kg soil dw
Extrapolation method:
assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

The information concerning the aquatic toxicity of Tetramethyltrimethylenediamine (TMPDA) are summarized hereafter:

Acute toxicity to fish: LC50_96h > 100 mg/L

Acute toxicity to daphnia: EC50_48h = 52.8 mg/L

Long-term toxicity to daphnia: NOEC = 0.44 mg/L

Toxicity to algae: ErC50_72h = 10 mg/L and ErC10_72h = 1.1 mg/L

TMPDA is not readily biodegradable and has a log Kow < 1.

Based on these results, here is the classification for TMPDA:

Dangerous substance directive: R51/53

Classification Labelling & Packaging: H411 (Chronic 2)