Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

A LLNA study according to OECD 429 and EC. B.42 guidelines was performed. The SI values calculated for the substance concentrations 10, 25 and 50% were 1.0, 1.4 and 1.1 respectively. Since there was no indication that the test substance elicits an SI ≥ 3 when tested up to 50%, Silicic acid (H2Si2O5), barium salt (1:1), lead-doped was considered not to be a skin sensitizer in the LLNA. It was established that the EC3 value (the estimated test substance concentration that will give a SI =3) (if any) exceeds 50%.

Migrated from Short description of key information:
The substance showed to be not sensitising in a LLNA study.

Justification for classification or non-classification

Based on these available data, Silicic acid(H2Si2O5), barium salt(1:1), lead-doped does not have to be classified for skin sensitisation according to Directive 67/548/EC or the CLP Regulation.