Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
An acute daphnia study was performed under semi-static testing conditions in accordance with OECD TG 202. Groups of twenty daphnia (less than 24 hours old) were exposed for 48 hours to loading rates of 1.0, 0.50, 0.25, 0.125 and 0.065 test substance/mg/L (spacing factor 2) and a control. Due to poor water solubility water accommodated fractions were prepared at test start and each renewal. The initial concentrations and the maintenance of the exposure concentrations during the test were verified in the analytical part by measuring 2,2-dimethoxyethyl)benzene, which showed to be stable during the experiment. All reported results refer to nominal concentrations (loading rate) since a supersaturated stock solution via a water accommodated fraction was prepared. After 48 hours at 1 mg/l 55% of the Daphnia were immobilised, the extrapolated 48-hour EL50 value was determined to be > 1.0 mg test item/L, at which 50% of the Daphnia were immobilised with an extrapolated EL50 of 1.16 mg test item/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 1 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
