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Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13-10-2020/3-11-2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2021
Report date:
2021

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
30 May 2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
1,6-anhydro-β-D-glucose
EC Number:
207-855-0
EC Name:
1,6-anhydro-β-D-glucose
Cas Number:
498-07-7
Molecular formula:
C6H10O5
IUPAC Name:
(1R,2S,3S,4R,5R)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
Constituent 2
Chemical structure
Reference substance name:
Glycollaldehyde
EC Number:
205-484-9
EC Name:
Glycollaldehyde
Cas Number:
141-46-8
Molecular formula:
C2H4O2
IUPAC Name:
2-hydroxyacetaldehyde
Constituent 3
Reference substance name:
Organic acids
IUPAC Name:
Organic acids
Constituent 4
Reference substance name:
Ketones
IUPAC Name:
Ketones
Constituent 5
Reference substance name:
Phenols
IUPAC Name:
Phenols
Constituent 6
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
water
Constituent 7
Reference substance name:
Oligomers of sugars and anhydrosugars
IUPAC Name:
Oligomers of sugars and anhydrosugars
Test material form:
liquid: viscous

Results and discussion

Boiling point
Key result
Boiling pt.:
>= 63 - <= 149.71 °C
Atm. press.:
1 004 mBar

Any other information on results incl. tables

Observatio

Values Observations

Mass test item

Mass crucible (before measurement)

Mass crucible (after measurement)

Observations

First Measurement

2.44 mg

47.40 mg

46.92 mg

After the test the crucible was visually unchanged

Second Measurement

2.44 mg

47.40 mg

46.91 mg

After the test the crucible was visually unchanged

Third Measurement

2.51 mg

47.19 mg

46.74 mg

After the test the crucible was visually unchanged


Interpretation of the measurements

After the test the crucible was visually unchanged. Three DSC measurements were performed.

In all measurements a flat broad endothermic event with slightly lowered baseline was detected, this behavior can be assumed to be boiling. Therefore, the boiling point is indicated in the range with peak maximum and was evaluated with event markers for marking start and end as well as peak maximum ((for safety reasons the lowest peak maximum was given).
The Peak maximum could be the boiling point of the main component because the test item is a UVCB substance.

Presentation of results
All results are presented in the following table.

Beginning of boiling process

in °C (event mark)

in K

1 Determination

63.66

336.81

2 Determination

63.00

336.15

3 Determination

63.38

336.53

Min

63.00

336.15

 

 

 

Peak max

in °C (onset)

in K

1 Determination

114.78

387.93

2 Determination

106.63

379.78

3 Determination

125.63

398.78

Min

106.63

379.78

 

 

 

End of boiling process

in °C (event mark)

in K

1 Determination

149.71

422.86

2 Determination

149.30

422.45

3 Determination

149.49

422.64

Max

149.71

422.86

Validity

The validity criteria apply only if the test was determined using DSC.
As the test item is a mixture (UVCB) a boiling range can be expected. Therefore, the boiling range is stated for the test item.

Applicant's summary and conclusion

Conclusions:
A range of 63.00 °C – 149.71 °C (336.15 K – 422.86 K) as boiling process with a lowest peak maximum of 106.63 °C (379.78 K)
Executive summary:

The determination of the boiling point of Pyrolytic Sugar was performed via DSC (differential scanning calorimetry. In all runs one flat broad event was detected. The event is endotherm and is stated as the boiling point.

Based on the pre-test a boiling point was determined under these circumstances as the endothermic event giving in a range of:

63.00 °C (336.15 K) to 149.71 (422.86 K)with a peak maximum of 106.63 °C (379.78 K) (for safety reasons the lowest peak maximum was given)
These values are the results from three independent determinations.

No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.

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