Registration Dossier
Registration Dossier
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EC number: 701-325-7 | CAS number: -
Bioaccumulation: terrestrial
Administrative data
Link to relevant study record(s)
Description of key information
Bioaccumulation poses no concern.
Key value for chemical safety assessment
Additional information
- ATSDR Agency for Toxic Substances and Disease Registry (2008). Draft Toxicological Profile for Manganese. U.S. Department of Health and Human Services, Public Health Service, Atlanta, Georgia, U.S.A. 539 p
- Brault N, Loranger S, Courchesne F, et al (1994). Bioaccumulation of manganese by plants: Influence of MMT as a gasoline additive. Sci Total Environ 153:77-84.
- Lönnerdal B (1997). Effects of milk and milk components on calcium, magnesium, and trace element absorption during infancy. Physiol Rev 77:643 -69.
- ATSDR Agency for Toxic Substances and Disease Registry (2008). Toxicological Profile for Aluminum. U.S. Department of Health and Human Services, Public Health Service, Atlanta, Georgia, U.S.A. 357 p
- DOE U.S. Department of Energy (1984). A review and analysis of parameters for assessing transport of environmentally released radionuclides through agriculture. U.S. DOE. ORNL-5786.
Manganese
The following summary is taken from ATSDR (2008):
„Bioaccumulation of manganese by plants was examined using oats (Avena nova) and beans (Phaseolus vularis) (Brault et al 1994). These plants were grown in sandy and organic soil at a control site (greenhouse) and at two outdoor sites near <20,000 and 132,000 vehicles/day respectively. The highest manganese accumulation was found in the fruits and stems of oats grown in the organic and sandy soils at the station with the highest traffic density. Lönnerdal (1997) reported that infant formulas contain 30– 75 ppb (0.03–0.075 ppm) manganese, as compared to concentrations of 3–10 ppb (0.003–0.01 ppm) in breast milk and 30 ppb (0.03 ppm) in cow's milk.“
High exposure of plant was correlated with higher manganese contents. Breast milk contained a third of the cow milk level indicating depletion along terrestrial food chains.
Aluminium
The following summary is taken from ATSDR (2008):
Aluminium does not appear to accumulate to any significant degree in cow's milk or beef tissue and is, therefore, not expected to undergo biomagnification in terrestrial food chains (DOE 1984). Transfer coefficients of 0.0002 (kg/day)-1 for uptake into milk and 0.0015 (kg/day)-1 for uptake into beef tissue have been reported (DOE 1984). The transfer coefficients represent the fraction of daily aluminium intake in feed that is transferred to a kilogram of milk or beef muscle. Based upon the above values, aluminium is not transferred to beef muscle or milk from feed to any appreciable extent and therefore would not be expected to bioaccumulate in terrestrial food chains (ATSDR 2008).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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