Registration Dossier

Diss Factsheets

Physical & Chemical properties

Boiling point

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2021-01-26 to 2021-02-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
no
GLP compliance:
no
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
237 °C
Atm. press.:
1 013 hPa
Decomposition:
no

Results of the DSC-measurement

Sample weight / mg

Onset of Effect / °C

Range of effect / °C

Weight loss / mg

Atmospheric pressure / hPa

10.04

2.55

238.88

0 – 20 (endo)

200 – 250 (endo)

10.04

1007.0

11.26

2.71

236.04

0 – 20 (endo)

210 – 250 (endo)

11.26

988.9

The test item showed a second endothermic signal in the temperature range of 200 – 250 °C. During the verification measurements with the photocell detection method it was observed, that at approx. 220 °C a first bubble starts to rise. At approx. 230 °C the frequency of bubbles rising increased. At 236.3 °C the boiling criterion with a frequency of 0.6 Hz was reached. The liquid remained colorless throughout the measurement.

For the correction of the boiling temperatures to standard pressure the test item was assigned to chemical group 8 (e.g. Ethanol; Propanol) According to appendix 7.2 a correction value φ = 6.4 was used for the temperature range from 230 °C to 240 °C. Therefore, the onset temperatures corrected to atmospheric pressure (1013 hPa) are 237.1 °C and 236.9 °C.

As the onset temperatures in the DSC measurements do not deviate by more than 0.5 K from their mean value of 237.0 °C, this temperature can be used as boiling point, which could be confirmed by the capillary method (236.3 °C).

No further thermal effects were observed up to the test end temperature of 500 °C.

Conclusions:
The boiling point of the test item was determined to be 237 °C.
Executive summary:

An experimental study was conducted according to Regulation (EC) No 440/2008 Method A.2. and OECD Test Guideline No. 103 using differential scanning calorimetry. For the verification of the DSC-measurements a further measurement with the photo cell detection method was performed. The test item showed a second endothermic signal in the temperature range of 200 - 250 °C. During the verification measurements with the photocell detection method it was observed, that at approx. 220 °C a first bubble starts to rise. Therefore, the onset temperatures of the DSC measurements are assigned to the boiling point. The mean boiling point corrected to atmospheric pressure (1013 hPa) is 237 °C.

Description of key information

The boiling point of the test item was determined to be 237 °C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
237 °C

Additional information

An experimental study was conducted according to Regulation (EC) No 440/2008 Method A.2. and OECD Test Guideline No. 103 using differential scanning calorimetry. For the verification of the DSC-measurements a further measurement with the photo cell detection method was performed. The test item showed a second endothermic signal in the temperature range of 200 - 250 °C. During the verification measurements with the photocell detection method it was observed, that at approx. 220 °C a first bubble starts to rise. Therefore, the onset temperatures of the DSC measurements are assigned to the boiling point. The mean boiling point corrected to atmospheric pressure (1013 hPa) is 237 °C.