Registration Dossier
Registration Dossier
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EC number: 604-446-2 | CAS number: 144850-45-3
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-one
- EC Number:
- 604-446-2
- Cas Number:
- 144850-45-3
- Molecular formula:
- C14H16O3
- IUPAC Name:
- (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-one
- Test material form:
- solid: particulate/powder
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- not specified
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
- Test performance:
- All the validity criteria were successfull exept the biodegradability in the toxicity control. Therefore, the test item was inhibitory at the testes concentration of 100 mg/L.
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- Based on ThODNH4, the 10-day window failed and the degradation rate of the test item D305 is zero fater 28 days of incubation.
BOD5 / COD results
BOD5 / COD
- Key result
- Parameter:
- ThOD
- Value:
- 0 g O2/g test mat.
- Results with reference substance:
- % biodegradation with reference item is >68 afater 28 days of incubation
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Based on ThODNH4, the 10-day window failed and the degradation rate of the test item D305 is zero fater 28 days of incubation.
- Executive summary:
Biodegradability was performed according OECD 301F guideline. Based on ThODNH4, the 10-day window failed and the degradation rate of the test item D305 is zero fater 28 days of incubation.
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