Registration Dossier
Registration Dossier
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EC number: 233-477-0 | CAS number: 10193-36-9
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test: determination of partition coefficient of PEG
- Short description of test conditions: Partition coefficient of PEG 400 were determined in quadruplicate for water and hydrophobic solvents. For each run, 33 g of PEG 400 were dissolved in 110 ml of water. Polyethylene glycol solution was added to 110 ml of organic solvent in a 500-ml reaction bottle. The PEG content of the organic phase and water phase was determined using high-performance liquid chromatography (HPLC) - Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. -3.05
- Temp.:
- 25 °C
- pH:
- ca. 7
Reference
Description of key information
Taking in mind the real range of -1 > x < 8, the value of -1 has been used to calculate the predicted exposure.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1
- at the temperature of:
- 25 °C
Additional information
calculated.
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