Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 433-730-7 | CAS number: 23926-51-4 L-THREONINETHYLESTER
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Remarks:
- OECD 301F study performed
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study carried out in compliance with the OECD Principles of Good Laboratory Practice (GLP). The OECD Guideline 301F was followed and there were no deviations to study protocol. Validation criteria were fulfilled.
- Qualifier:
- according to guideline
- Guideline:
- other: OECD301F
- Deviations:
- no
- GLP compliance:
- yes
- Details on sampling:
- Aerobic respirometer. Contineuos measurement of oxygen consumption (CO2 production)
- Vehicle:
- no
- Test organisms (species):
- activated sludge
- Test type:
- static
- Limit test:
- no
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- yes
- Remarks:
- Sodium benzoate
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- > 20 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Details on results:
- No inhibition of the microorganisms was observed during the biodegradation test. Therefore the NOEC is determined to be > 20 mg/L (the concentration applied in the test)
- Conclusions:
- There was no inhibition of microorganisms at the concentration tested (20 mg/L). Therefore the NOEC is reported as > 20 mg/L
- Executive summary:
The Biodegradation of L-TEE was tested applying the OECD Guideline No. 301F. The toxicity control showed no toxicity and is therefore interpretated as a NOEC for microorganisms. The NOEC is therefore reported as > 20 mg/L
Reference
Description of key information
No inhibition of the microorganisms was observed during the biodegradation test. Therefore the NOEC is determined to be > 20 mg/L (the concentration applied in the test)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 20 mg/L
Additional information
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