Ethyl L-threoninate

Toxicity to microorganisms

Link to relevant study record(s)

Reference

Endpoint:

toxicity to microorganisms, other

Remarks:

OECD 301F study performed

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study carried out in compliance with the OECD Principles of Good Laboratory Practice (GLP). The OECD Guideline 301F was followed and there were no deviations to study protocol. Validation criteria were fulfilled.

Qualifier:

according to guideline

Guideline:

other: OECD301F

Deviations:

no

GLP compliance:

yes

Details on sampling:

Aerobic respirometer. Contineuos measurement of oxygen consumption (CO2 production)

Vehicle:

no

Test organisms (species):

activated sludge

Test type:

static

Limit test:

no

Total exposure duration:

28 d

Reference substance (positive control):

yes

Remarks:

Sodium benzoate

Key result

Duration:

28 d

Dose descriptor:

NOEC

Effect conc.:

> 20 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth inhibition

Details on results:

No inhibition of the microorganisms was observed during the biodegradation test. Therefore the NOEC is determined to be > 20 mg/L (the concentration applied in the test)

Conclusions:

There was no inhibition of microorganisms at the concentration tested (20 mg/L). Therefore the NOEC is reported as > 20 mg/L

Executive summary:

The Biodegradation of L-TEE was tested applying the OECD Guideline No. 301F. The toxicity control showed no toxicity and is therefore interpretated as a NOEC for microorganisms. The NOEC is therefore reported as > 20 mg/L

Description of key information

No inhibition of the microorganisms  was observed during the biodegradation test. Therefore the NOEC is determined to be > 20 mg/L (the concentration applied in the test)

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:

20 mg/L