Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 685-617-9 | CAS number: 1099648-69-7
Endpoint summary
Administrative data
Description of key information
Three acute experimental studies and three QSAR predictions are available to assess the aquatic toxicity of the registered substance.
For aquatic invertebrates, the experimental study, performed on Daphnia magna, was not considered reliable due to major methodological deficiencies. Therefore, a QSAR prediction for this endpoint was performed using iSafeRat® High-Accuracy-Quantitative Structure-Activity Relationship (KREATIS, 2019) and the 48h-EC50 value, used as key data, was predicted at 136 mg/L.
For algae and fish, the experimental studies, performed on Desmodesmus subspicatus and Gobiocypris rarus respectively, were considered reliable. In these studies, no toxicity was observed up to 100 mg/L for both trophic levels. However, in order to obtain quantitative toxicity values, QSAR predictions were performed using iSafeRat® High-Accuracy-Quantitative Structure-Activity Relationship (KREATIS, 2019). The 72h-ErC50 value for algae and 96h-LC50 value for fish, used as key data, were predicted at 145 mg/L and 164 mg/L, respectively.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
