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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2020-09-29
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Key result
Percentile:
D10
Mean:
6.02 µm
Remarks on result:
other: St. dev. not reported
Key result
Percentile:
D50
Mean:
14.1 µm
Remarks on result:
other: St. dev. not reported
Key result
Percentile:
D90
Mean:
30.7 µm
Remarks on result:
other: St. dev. not reported

The primary particles of the test substance were observed by the wet method. The values for sizes at 10 %, 50 % and 90 % (D10, D50 and D90) were 6.02 µrn, 14.1 µm and 30.7 µrn, respectively. By the dry method without compressed air, the agglomerates of test substance (mode size 63 - 72 µm) were observed. Although some agglomerates were finely dispersed with applying compressed air (0.40 MPa), they could not be completely dispersed.

Conclusions:
The D10, D50 and D90 percentile were determined as D10 = 6.02 µm, D50 = 14.1 µm and D90 = 30.7 µm, respectively.
Executive summary:

A study was conducted according to CIPAC MT 187 to determine the particle size distribution of the test item by laser diffraction. By the dry method without compressed air, the agglomerates of test substance (mode size 63 - 72 µm) were observed. The agglomerates could not be completely dispersed by applying compressed air. Therefore, the primary particles of the test substance were observed by the wet method. The D10, D50 and D90 percentile were determined as D10 = 6.02 µm, D50 = 14.1 µm and D90 = 30.7 µm, respectively.

Description of key information

The D10, D50 and D90 percentile were determined as D10 = 6.02 µm, D50 = 14.1 µm and D90 = 30.7 µm, respectively.


 

Additional information

A study was conducted according to CIPAC MT 187 to determine the particle size distribution of the test item by laser diffraction. By the dry method without compressed air, the agglomerates of test substance (mode size 63 - 72 µm) were observed. The agglomerates could not be completely dispersed by applying compressed air. Therefore, the primary particles of the test substance were observed by the wet method. The D10, D50 and D90 percentile were determined as D10 = 6.02 µm, D50 = 14.1 µm and D90 = 30.7 µm, respectively.