Registration Dossier
Registration Dossier
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EC number: 855-895-8 | CAS number: 212908-67-3
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted 27 July 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
Test material
- Reference substance name:
- 2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]benzamide
- EC Number:
- 855-895-8
- Cas Number:
- 212908-67-3
- Molecular formula:
- C27H47NO5
- IUPAC Name:
- 2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]benzamide
- Test material form:
- solid: bulk
- Details on test material:
- Batch EP15C02132
Benzamide,N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy-
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 15.2 µg/L
- Temp.:
- 20 °C
- pH:
- 7
Any other information on results incl. tables
Sample of the Equilibrium |
Phytosphingosine SLC [microgram/L] at 0.4 mL/min
|
Phytosphingosine SLC [microgram/L] at 0.2 mL/min |
Overall [microgram/L]
|
1 |
16.9 |
14.6 |
- |
2 |
17.9 |
13.1 |
- |
3 |
16.9 |
13.4 |
- |
4 |
16.2 |
12.5 |
- |
| 5 | 17.4 | 13.3 | - |
| mean | 17.1 | 13.4 | 15.2 |
| Deviation [%] | 11 | 17 | 27 |
Standard deviation |
0.7 | 0.8 | |
Applicant's summary and conclusion
- Conclusions:
- The water solubility of Phytosphingosine SLC is 15.2 microgram/L at 20°C (pH 7).
- Executive summary:
The water solubility of Phytosphingosine SLC was determined according to OECD guideline 105, 27 July 1995, using the column eluation method. The water solubility of Phytosphingosine SLC is 15.2 microgram/L at 20°C (pH 7).
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